People often ask me what the clinical trial is doing for Evie's bones. We had some x-rays done at Evie's orthopedic appointment yesterday so I thought I would show you for yourselves! I requested a disc of Evie's studies that have been done, I'm sure you will notice the difference:
x-ray of Evie's right leg, taken 9/20/2009 at 1 day old.
bone is undermineralized, short, bowed, and "disorganized" as her doc says.
x-ray of Evie's right leg, taken 7/27/2011 at 22 months of age.
bones are still undermineralized, yet there is lengthening, straightening, new bone forming, and organization into "normal"-ish, functioning leg bones!
Her doctor remarked that these two x-rays don't even look like they are from the same child! She has had such tremendous improvement in the past 22 months.
For those of you who are interested, in the top photo, the ends of Evie's bones are there, you just can't see them because of how undermineralized they are. They are basically cartilage that hasn't turned to bone yet. The lines in the more recent x-ray are stress points, or possibly micro-fractures from when she was still in utero or were caused at birth. When she gets more mobile these will be the possible breaking points, although her mom seems to think she will surprise everyone and stay in tact (: You can see the woman's hand in the more recent photo, this is what a more normally mineralized bone would look like, you can see Evie's are more gray, showing the undermineralization.
Love you friends! Thank you for your wonderful comments on Evie's walking video, she is practicing every day and gets so excited to show off her new skills (: She walked around a little when her friends were over today, it was so much fun to see her eye-level with kids her age.